A & T Respiratory Medicine

  Background  The mortality rate of community-acquired pneumonia (CAP) is high in adult patients. The highest mortality has been registered in patients in the older age group with a steady rise in the incidence of morbidity in younger people of working age.  There is a need to focus research on the role of neutrophils in the pathogenesis of pneumonia as CAP largely determines the outcomes of the same. This research is aimed at evaluating the indices of neutrophils oxidized-modified proteins and oxidative stress in patients with CAP, depending on the severity, and comparison of the frequency of neutrophil extracellular traps responsible for causing the progress of pneumonia.  Introduction The development of CAP is diverse among different patients. It is dependent on the etiology and the pathways of penetration of the microorganisms into the lungs.  The evaluation of the changes in the metabolic and functional status of neutrophils could be one of the urgent areas of research, as their

  Objective The soluble form of guanylate cyclase (sGC) stimulator riociguat has been approved for the management of patients with PAH (pulmonary arterial hypertension). It is also approved for the treatment of inoperable or recurrent/persistent chronic thromboembolic pulmonary hypertension after its safety and efficacy were assessed during the phase 3 randomized trials.  This EXPERT (EXPosurE Registry RiociguaT) study in patients with pulmonary hypertension is designed to assess the long-term safety of this medication in clinical practice. Methods EXPERT is an international, non-interventional prospective, multicenter, uncontrolled, cohort study of patients who were administered riociguat. During this study, patients were followed up for at least one year and up to four years from the enrollment or for 30 days after they stopped riociguat treatment.  The safety outcomes were related to the serious adverse events (SAEs) and adverse events (AEs) coded using Medical Dictionary for the Sy

  CLICK HERE TO JOIN It is common for physicians and nurses to face ethical dilemmas every day while providing care to patients, especially those with critical illnesses. The situations where the answer can be “right” are very rare in such cases.  This is especially more common during EOL (end-of-life) care, where the patient and caregivers might experience extreme emotions like grief, sadness, and loss. Oncologists often have to act as mediators through such difficult moments by advocating for their patients and connecting their caregivers with resources that would help them during the challenging phase. During EOL care, the ethical dilemma may arise due to situations like patient's independence being compromised, communication breakdowns, lack of effective symptom management, shared decision making, and non-beneficial care.  Physicians often have to navigate through such ethical dilemmas by suggesting the best possible treatment and advice while allowing patients and their family

  CLICK HERE TO JOIN   Medical negligence refers to the negligence or an act of recklessness by a healthcare professional that can result in foreseeable damage to the patient.  Medical negligence also includes any act of misconduct by a doctor or medical practitioner by not providing adequate care resulting in the breach of his duties and causing harm to the patients, who are considered his consumers.  A medical professional is deemed to possess the knowledge and expertise in the field of medicine to help a patient get healed. The patients expect the physician to be careful and diligent while performing these duties. Medical negligence involves improper, negligent, or unskilled treatment even by dentists, nurses, pharmacists, and other healthcare professionals. Medical negligence may cause serious harm to the patient’s health and even result in his death. The liability in such cases lies with the physician as well as the hospital, pharmacists, nurses, laboratory technicians, and other

  CLICK HERE TO JOIN ME It is estimated that the occurrence of adverse events associated with unsafe healthcare is one of the leading causes of death and disabilities in the world. It is intriguing to know that even in high-income countries about one in ten patients is likely to develop complications while receiving hospital care.  The harm may be caused due to a range of factors with about 50 percent of them being preventable. This marks the importance of ensuring optimum patient safety and preventing medical errors in healthcare to reduce the incidences of patient harm.  Patient safety as an important healthcare discipline has emerged with the rising complexity in the healthcare systems and the resulting increase in the incidences of patient harm while in the healthcare facilities.  Patient safety is aimed at preventing and reducing the risks and medical errors during the provision of healthcare services. One of the cornerstones of this discipline is continuous improvements based on

  CLICK HERE TO JOIN ME Lung and airway infections are commonly referred to as pulmonary or respiratory infections. Chronic bronchitis, COPD, influenza, tuberculosis, and pneumonia are some of the major forms of respiratory infections.  Nasopharyngeal infections that result in nasal discharge, bronchitis that leads to cough and sputum, and pneumonia that leads to cough with sputum can also increase the respiratory rate and lead to breathing difficulties.  There are several viruses that contribute to the increased incidence of bronchitis, while bacteria are known to contribute to pneumonia.  These infections usually spread from infected patients to healthy people through contaminated droplets released into the air when the infected person sneezes and coughs. These respiratory conditions are the leading causes of mortality and morbidity from infectious diseases across the world. Nearly four million people are estimated to die due to acute respiratory infection every year. About 98% of th